Two Classes of p38alpha MAP Kinase Inhibitors Having a Common Diphenylether Core but Exhibiting Divergent Binding Modes

PDB Details

PDB ID
1ZZ2
Status
CURRENT
Deposition Date
2005-06-13
Modification Date
2009-02-24
Pubmed ID
16169718
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
Q16539

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 0 24
A C EDI 1 14
A C EDI 3 12
A C LBP 5 9
A C PDIG 6 6
A C LBP 7 3
A N MT3 1 16
A N MT3 2 16
A N PIF 3 9
A N ATP 4 8
A N DFG 6 6
A N ATP 9 4

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Legend

Color Name Hit Count