The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor

PDB Details

PDB ID
2B7A
Status
CURRENT
Deposition Date
2005-10-04
Modification Date
2009-02-24
Pubmed ID
16174768
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
O60674

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A N MT3 0 24
A N MT3 2 15
A N ATP 3 13
B C PDIG 5 8
B N MT3 0 21
B N PIF 2 12
B N ATP 5 7
B N MPP 6 6
B N MT3 9 2

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Legend

Color Name Hit Count