STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY

PDB Details

PDB ID
2BRO
Status
CURRENT
Deposition Date
2005-05-09
Modification Date
2009-02-24
Pubmed ID
15974586
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
O14757

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 4 9
A C EDI 7 6
A C PDIG 8 3
A N ATP 1 18
A N MPP 2 15
A N MT3 3 14
A N ATP 4 10
A N MPP 5 8
A N ATP 8 2

Mapping Results Viewer

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Legend

Color Name Hit Count