DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN

PDB Details

PDB ID
2C5O
Status
CURRENT
Deposition Date
2005-10-30
Modification Date
2009-02-24
Pubmed ID
16492568
Method
X-RAY DIFFRACTION
Resolution (Å)
2.1
UniProt Accessions
P24941

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 0 18
A N ATP 0 25
A N PIF 1 19
A N MPP 2 12
A N DFG 3 8
A N ATP 5 7
A N MT3 6 6
C C LBP 0 17
C C LBP 7 6
C N ATP 0 25
C N PIF 1 21
C N MT3 2 11
C N DFG 4 6
C N MPP 5 6
C N ATP 6 5
C N ATP 8 3

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Legend

Color Name Hit Count