DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN

PDB Details

PDB ID
2C5V
Status
CURRENT
Deposition Date
2005-11-02
Modification Date
2009-02-24
Pubmed ID
16492568
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
P24941

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 0 16
A C LBP 5 6
A N ATP 0 18
A N PIF 1 17
A N MPP 2 15
A N ATP 3 12
A N ATP 6 3
A N ATP 7 3
C C LBP 0 19
C C LBP 5 10
C C EDI 9 2
C N PIF 0 16
C N MPP 1 14
C N ATP 3 11
C N ATP 4 11
C N ATP 7 5

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Legend

Color Name Hit Count