DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN

PDB Details

PDB ID
2C5X
Status
CURRENT
Deposition Date
2005-11-03
Modification Date
2009-02-24
Pubmed ID
16492568
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
P24941

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 0 15
A C LBP 7 4
A C PDIG 12 2
A N PIF 0 21
A N ATP 1 15
A N MPP 2 14
A N ATP 3 11
A N ATP 5 5
A N DFG 6 4
C C EDI 3 10
C C EDI 4 8
C C LBP 5 7
C C LBP 6 6
C C AAS 8 2
C N PIF 0 21
C N ATP 1 13
C N MPP 4 7
C N ATP 5 6
C N DFG 9 2

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Legend

Color Name Hit Count