4-ARYLAZO-3,5-DIAMINO-1H-PYRAZOLE CDK INHIBITORS: SAR STUDY, CRYSTAL STRUCTURE IN COMPLEX WITH CDK2, SELECTIVITY, AND CELLULAR EFFECTS

PDB Details

PDB ID
2CLX
Status
CURRENT
Deposition Date
2006-05-02
Modification Date
2009-02-24
Pubmed ID
17064068
Method
X-RAY DIFFRACTION
Resolution (Å)
1.8
UniProt Accessions
P24941

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C MT3 0 20
A C CMP 1 17
A C LBP 6 5
A C PDIG 9 2
A N ATP 0 32
A N MT3 1 22
A N MT3 2 22
A N MT3 3 8
A N MT3 5 3

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Legend

Color Name Hit Count