Structure of the Kinase Domain of an Imatinib-Resistant Abl Mutant in Complex with the Aurora Kinase Inhibitor VX-680

PDB Details

PDB ID
2F4J
Status
CURRENT
Deposition Date
2005-11-23
Modification Date
2009-02-24
Pubmed ID
16424036
Method
X-RAY DIFFRACTION
Resolution (Å)
1.91
UniProt Accessions
P00519

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 5 7
A C CMP 7 5
A C EDI 9 2
A C CMP 10 2
A N ATP 0 25
A N MPP 1 23
A N ATP 4 9
A N ATP 7 3
A N MT3 9 1

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Legend

Color Name Hit Count