Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity

PDB Details

PDB ID
2GMX
Status
CURRENT
Deposition Date
2006-04-07
Modification Date
2009-02-24
Pubmed ID
16759099
Method
X-RAY DIFFRACTION
Resolution (Å)
3.5
UniProt Accessions
P45983

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DEF 0 16
A C DRS 4 9
A C EDI 7 6
A C DEF 10 3
A C EDI 12 2
A N ATP 0 21
A N PIF 1 18
A N ATP 3 9
A N DFG 7 4
A N MT3 8 4
B C DEF 0 15
B C DEF 1 15
B C DRS 5 6
B C EDI 6 6
B C DEF 7 5
B C LBP 9 2
B N ATP 0 19
B N PIF 1 18
B N DFG 5 8
B N MT3 6 6
B N ATP 8 4

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Legend

Color Name Hit Count