X-ray Crystal Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain

PDB Details

PDB ID
2GQG
Status
CURRENT
Deposition Date
2006-04-20
Modification Date
2011-07-13
Pubmed ID
16740718
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P00519

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 5 8
A C AAS 6 6
A C CMP 7 4
A C CMP 10 1
A N ATP 0 21
A N MPP 1 18
A N ATP 3 13
A N DFG 5 9
A N ATP 6 5
B C CMP 5 8
B C CMP 6 6
B C DRS 10 2
B N ATP 0 20
B N MPP 1 19
B N ATP 3 12
B N MT3 6 4
B N MPP 8 2

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Legend

Color Name Hit Count