Discovery of Potent, Highly Selective, and Orally Bioavailable Pyridine Carboxamide C-jun NH2-terminal Kinase Inhibitors

PDB Details

PDB ID
2H96
Status
CURRENT
Deposition Date
2006-06-09
Modification Date
2011-07-13
Pubmed ID
16854050
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
P45983

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 28
A C PDIG 1 15
A C DEF 2 13
A C DEF 5 8
A C DRS 6 5
A C PDIG 7 4
A C LBP 8 2
A N PIF 0 18
A N ATP 1 18
A N MT3 3 11
A N MT3 7 3
B C DEF 0 21
B C EDI 1 17
B C EDI 3 9
B C DRS 6 5
B C PDIG 7 5
B C DRS 9 4
B C LBP 10 3
B N PIF 1 16
B N ATP 3 16
B N MT3 6 3

Mapping Results Viewer

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Legend

Color Name Hit Count