Crystal Structure of Inactive Conformation Abl Kinase Catalytic Domain Complexed with Type II Inhibitor

PDB Details

PDB ID
2HIW
Status
CURRENT
Deposition Date
2006-06-29
Modification Date
2009-02-24
Pubmed ID
16873026
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
P00519

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 4 10
A C DFG 8 3
A N MPP 0 22
A N ATP 1 18
A N ATP 2 15
A N MPP 5 10
B C AAS 4 8
B C DFG 8 4
B C DFG 10 3
B N MPP 0 22
B N ATP 1 17
B N ATP 2 17
B N MPP 6 3

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Legend

Color Name Hit Count