Crystal structure of Src kinase domain in complex with covalent inhibitor PD168393

PDB Details

PDB ID
2HWP
Status
CURRENT
Deposition Date
2006-08-01
Modification Date
2009-02-24
Pubmed ID
17334377
Method
X-RAY DIFFRACTION
Resolution (Å)
2.48
UniProt Accessions
P00523

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 15
A C CMP 3 10
A C CMP 8 3
A C AAS 10 2
A N MT3 1 17
A N MPP 2 16
A N DFG 3 15
A N MPP 4 12
A N MT3 5 4
A N ATP 7 3
B C EDI 0 16
B C AAS 1 15
B C CMP 4 11
B C PDIG 8 5
B C DFG 9 4
B N PIF 0 27
B N MPP 1 20
B N MPP 3 14
B N DFG 5 6
B N ATP 6 3

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Legend

Color Name Hit Count