Human Abl kinase domain in complex with imatinib (STI571, Glivec)

PDB Details

PDB ID
2HYY
Status
CURRENT
Deposition Date
2006-08-08
Modification Date
2009-02-24
Pubmed ID
17164530
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P00519

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 2 13
A C DFG 6 6
A N MPP 1 16
A N ATP 2 16
A N ATP 3 15
A N ATP 4 10
A N MPP 5 5
A N MPP 7 2
B C DFG 5 8
B C DFG 7 4
B N ATP 0 28
B N MPP 1 19
B N ATP 3 13
C C PDIG 3 12
C C DFG 6 5
C C DFG 7 5
C C AAS 9 4
C N ATP 0 20
C N ATP 1 13
C N ATP 2 13
C N MPP 3 12
C N MPP 4 9
C N MPP 6 6
C N MPP 7 5
D C DFG 6 4
D C DFG 7 3
D N ATP 1 18
D N MPP 2 18
D N ATP 3 15
D N ATP 5 4
D N ATP 6 3

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Legend

Color Name Hit Count