Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

PDB Details

PDB ID
2NP8
Status
CURRENT
Deposition Date
2006-10-26
Modification Date
2009-09-01
Pubmed ID
17157005
Method
X-RAY DIFFRACTION
Resolution (Å)
2.25
UniProt Accessions
O14965

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 33
A C CMP 1 18
A C EDI 2 12
A C AAS 6 4
A N MPP 0 26
A N ATP 1 16
A N MT3 2 16
A N PIF 4 12
A N MT3 6 4

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Legend

Color Name Hit Count