Evolution of a highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor

PDB Details

PDB ID
2P4I
Status
CURRENT
Deposition Date
2007-03-12
Modification Date
2009-02-24
Pubmed ID
17253678
Method
X-RAY DIFFRACTION
Resolution (Å)
2.5
UniProt Accessions
Q02763

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 7 4
A N MT3 0 23
A N PIF 1 17
A N MPP 3 16
A N ATP 4 12
B N MT3 1 18
B N ATP 3 14
B N PIF 4 14

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Legend

Color Name Hit Count