Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a] [1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities

PDB Details

PDB ID
3BE9
Status
CURRENT
Deposition Date
2007-11-16
Modification Date
2009-02-24
Pubmed ID
18055206
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
P28523

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 21
A C EDI 5 7
A C EDI 9 3
A C DRS 10 3
A N ATP 2 15
A N PIF 3 12
A N PIF 4 7
A N DFG 6 4
A N MPP 7 3

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count