Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52

PDB Details

PDB ID
3BPR
Status
CURRENT
Deposition Date
2007-12-19
Modification Date
2010-05-19
Pubmed ID
19028587
Method
X-RAY DIFFRACTION
Resolution (Å)
2.8
UniProt Accessions
Q12866

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 3 12
A C DRS 4 9
A N MPP 0 19
A N MT3 2 12
A N ATP 3 9
A N MPP 4 8
A N MT3 6 5
A N MT3 10 2
A N ATP 11 2
A N MPP 12 2
B C CMP 2 14
B C DRS 6 9
B N MPP 0 17
B N MPP 1 15
B N ATP 3 12
B N MT3 4 11
B N MT3 6 7
B N MPP 8 3
B N ATP 9 2
B N MT3 10 2
C C CMP 4 10
C C DRS 6 9
C C CMP 9 2
C N MPP 0 18
C N MPP 2 18
C N DFG 3 10
C N ATP 4 7
C N MT3 5 6
C N MT3 6 5
C N MPP 8 3
C N ATP 9 3
D C CMP 2 13
D C DRS 6 10
D N MPP 0 22
D N MPP 1 18
D N ATP 3 9
D N DFG 5 7
D N MT3 6 4
D N MT3 7 3
D N MPP 8 2

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Legend

Color Name Hit Count