Human ABL kinase in complex with nilotinib

PDB Details

PDB ID
3CS9
Status
CURRENT
Deposition Date
2008-04-09
Modification Date
2009-02-24
Pubmed ID
15710326
Method
X-RAY DIFFRACTION
Resolution (Å)
2.21
UniProt Accessions
P00519

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 0 22
A C AAS 2 13
A C DFG 5 5
A C CMP 7 2
A C AAS 9 2
A N ATP 0 18
A N MPP 1 17
A N ATP 3 17
A N ATP 4 6
A N MPP 7 4
B C DRS 2 12
B C DFG 4 5
B C AAS 6 4
B C AAS 7 4
B C EDI 8 3
B C CMP 9 2
B C DFG 10 2
B C AAS 11 2
B N MPP 0 23
B N ATP 1 18
B N ATP 2 15
B N ATP 4 12
B N MPP 6 3
C C DFG 1 16
C C AAS 2 14
C C AAS 3 12
C C CMP 9 2
C N MPP 0 23
C N ATP 1 14
C N ATP 2 14
C N ATP 3 11
C N MPP 5 5
C N MPP 6 5
C N MT3 7 3
D C DRS 4 10
D C DFG 5 10
D C AAS 6 8
D C AAS 7 7
D N ATP 0 25
D N MPP 2 14
D N MT3 4 9
D N DFG 5 6

Mapping Results Viewer

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Legend

Color Name Hit Count