Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

PDB Details

PDB ID
3E87
Status
CURRENT
Deposition Date
2008-08-19
Modification Date
2011-07-13
Pubmed ID
19179070
Method
X-RAY DIFFRACTION
Resolution (Å)
2.3
UniProt Accessions
P31751

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 20
A C DRS 1 18
A C DRS 4 12
A C CMP 8 2
A N ATP 0 17
A N ATP 1 15
A N MT3 4 9
A N DFG 5 7
A N ATP 8 3
B C DRS 0 30
B C PDIG 1 20
B C DRS 3 12
B C CMP 5 4
B N ATP 0 20
B N ATP 1 16
B N DFG 5 6
B N MT3 6 5
B N ATP 8 3

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Legend

Color Name Hit Count