Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

PDB Details

PDB ID
3E88
Status
CURRENT
Deposition Date
2008-08-19
Modification Date
2011-07-13
Pubmed ID
19179070
Method
X-RAY DIFFRACTION
Resolution (Å)
2.5
UniProt Accessions
P31751

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 0 29
A C PDIG 1 17
A C DRS 3 9
A C PDIG 5 5
A C CMP 9 2
A N MT3 0 19
A N ATP 1 16
A N ATP 2 15
A N ATP 9 2
B C PDIG 0 21
B C DRS 1 16
B C DRS 4 11
B N ATP 1 15
B N ATP 2 14
B N ATP 8 2

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Legend

Color Name Hit Count