Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors

PDB Details

PDB ID
3E8D
Status
CURRENT
Deposition Date
2008-08-19
Modification Date
2014-11-19
Pubmed ID
19179070
Method
X-RAY DIFFRACTION
Resolution (Å)
2.7
UniProt Accessions
P31751

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 20
A C DRS 4 12
A C PDIG 7 3
A N ATP 0 23
A N ATP 1 16
A N ATP 5 6
B C PDIG 1 22
B C DRS 3 15
B N ATP 0 20
B N ATP 1 18
B N ATP 5 9
B N ATP 7 1

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Legend

Color Name Hit Count