Kinase Atlas

Crystal structures of the kinase domain of PKA in complex with ATP-competitive inhibitors

Chain	Terminus	Site	Consensus Site Rank	Consensus Site Population
A	C	DRS	2	14
A	C	PMP	3	7
A	C	PMP	4	6
A	C	PMP	8	1
A	N	ATP	1	14
A	N	ATP	2	14
A	N	PIF	3	10
A	N	MT3	6	5
A	N	DFG	7	4
B	C	DRS	0	26
B	C	PMP	2	13
B	C	PMP	5	8
B	N	DFG	1	15
B	N	ATP	2	15
B	N	PIF	4	9
B	N	DFG	5	6
B	N	MT3	8	2
E	C	PMP	2	16
E	C	PMP	5	5
E	N	ATP	1	16
E	N	PIF	2	13
E	N	ATP	4	12
E	N	PIF	7	2
E	N	DFG	9	2
I	C	PMP	1	18
I	C	DRS	4	9
I	C	PMP	5	7
I	N	ATP	0	16
I	N	ATP	3	9
I	N	PIF	5	7
I	N	ATP	7	6
I	N	DFG	9	3
L	C	PMP	2	15
L	C	DRS	3	11
L	C	PMP	5	5
L	N	MT3	0	14
L	N	PIF	3	10
L	N	DFG	4	10
L	N	ATP	5	9
L	N	ATP	7	4
L	N	MT3	8	3
P	C	PMP	4	9
P	C	PMP	8	2
P	N	ATP	1	16
P	N	ATP	2	12
P	N	PIF	3	10
P	N	DFG	9	2

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Color	Name	Hit Count

Chain	Terminus	Site	Consensus Site Rank	Consensus Site Population
A	C	DRS	2	14
A	C	PMP	3	7
A	C	PMP	4	6
A	C	PMP	8	1
A	N	ATP	1	14
A	N	ATP	2	14
A	N	PIF	3	10
A	N	MT3	6	5
A	N	DFG	7	4
B	C	DRS	0	26
B	C	PMP	2	13
B	C	PMP	5	8
B	N	DFG	1	15
B	N	ATP	2	15
B	N	PIF	4	9
B	N	DFG	5	6
B	N	MT3	8	2
E	C	PMP	2	16
E	C	PMP	5	5
E	N	ATP	1	16
E	N	PIF	2	13
E	N	ATP	4	12
E	N	PIF	7	2
E	N	DFG	9	2
I	C	PMP	1	18
I	C	DRS	4	9
I	C	PMP	5	7
I	N	ATP	0	16
I	N	ATP	3	9
I	N	PIF	5	7
I	N	ATP	7	6
I	N	DFG	9	3
L	C	PMP	2	15
L	C	DRS	3	11
L	C	PMP	5	5
L	N	MT3	0	14
L	N	PIF	3	10
L	N	DFG	4	10
L	N	ATP	5	9
L	N	ATP	7	4
L	N	MT3	8	3
P	C	PMP	4	9
P	C	PMP	8	2
P	N	ATP	1	16
P	N	ATP	2	12
P	N	PIF	3	10
P	N	DFG	9	2

Chain	Terminus	Site	Consensus Site Rank	Consensus Site Population
A	C	DRS	2	14
A	C	PMP	3	7
A	C	PMP	4	6
A	C	PMP	8	1
A	N	ATP	1	14
A	N	ATP	2	14
A	N	PIF	3	10
A	N	MT3	6	5
A	N	DFG	7	4
B	C	DRS	0	26
B	C	PMP	2	13
B	C	PMP	5	8
B	N	DFG	1	15
B	N	ATP	2	15
B	N	PIF	4	9
B	N	DFG	5	6
B	N	MT3	8	2
E	C	PMP	2	16
E	C	PMP	5	5
E	N	ATP	1	16
E	N	PIF	2	13
E	N	ATP	4	12
E	N	PIF	7	2
E	N	DFG	9	2
I	C	PMP	1	18
I	C	DRS	4	9
I	C	PMP	5	7
I	N	ATP	0	16
I	N	ATP	3	9
I	N	PIF	5	7
I	N	ATP	7	6
I	N	DFG	9	3
L	C	PMP	2	15
L	C	DRS	3	11
L	C	PMP	5	5
L	N	MT3	0	14
L	N	PIF	3	10
L	N	DFG	4	10
L	N	ATP	5	9
L	N	ATP	7	4
L	N	MT3	8	3
P	C	PMP	4	9
P	C	PMP	8	2
P	N	ATP	1	16
P	N	ATP	2	12
P	N	PIF	3	10
P	N	DFG	9	2

Chain	Terminus	Site	Consensus Site Rank	Consensus Site Population
A	C	DRS	2	14
A	C	PMP	3	7
A	C	PMP	4	6
A	C	PMP	8	1
A	N	ATP	1	14
A	N	ATP	2	14
A	N	PIF	3	10
A	N	MT3	6	5
A	N	DFG	7	4
B	C	DRS	0	26
B	C	PMP	2	13
B	C	PMP	5	8
B	N	DFG	1	15
B	N	ATP	2	15
B	N	PIF	4	9
B	N	DFG	5	6
B	N	MT3	8	2
E	C	PMP	2	16
E	C	PMP	5	5
E	N	ATP	1	16
E	N	PIF	2	13
E	N	ATP	4	12
E	N	PIF	7	2
E	N	DFG	9	2
I	C	PMP	1	18
I	C	DRS	4	9
I	C	PMP	5	7
I	N	ATP	0	16
I	N	ATP	3	9
I	N	PIF	5	7
I	N	ATP	7	6
I	N	DFG	9	3
L	C	PMP	2	15
L	C	DRS	3	11
L	C	PMP	5	5
L	N	MT3	0	14
L	N	PIF	3	10
L	N	DFG	4	10
L	N	ATP	5	9
L	N	ATP	7	4
L	N	MT3	8	3
P	C	PMP	4	9
P	C	PMP	8	2
P	N	ATP	1	16
P	N	ATP	2	12
P	N	PIF	3	10
P	N	DFG	9	2