Structure of AuroraA with pyridyl-pyrimidine urea inhibitor

PDB Details

PDB ID
3EFW
Status
CURRENT
Deposition Date
2008-09-10
Modification Date
2013-06-26
Pubmed ID
19062275
Method
X-RAY DIFFRACTION
Resolution (Å)
2.29
UniProt Accessions
O14965

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 29
A C EDI 2 10
A C DFG 3 8
A C PDIG 9 3
A C AAS 12 2
A N MPP 1 19
A N ATP 2 17
A N MT3 3 15
A N MT3 6 6
B C PDIG 1 16
B C PDIG 3 11
B C CMP 4 10
B C EDI 6 6
B C AAS 9 4
B N MT3 0 22
B N ATP 1 18
B N MPP 2 17
B N MT3 3 13
B N PIF 4 12

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Legend

Color Name Hit Count