Structure-based drug design of novel Aurora kinase A inhibitors: Structure basis for potency and specificity

PDB Details

PDB ID
3FDN
Status
CURRENT
Deposition Date
2008-11-26
Modification Date
2009-09-15
Pubmed ID
19140666
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
O14965

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 19
A C AAS 2 11
A C DFG 8 5
A C EDI 11 3
A C EDI 12 1
A N MPP 0 21
A N PIF 1 20
A N ATP 2 17
A N MT3 3 13

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Legend

Color Name Hit Count