Equally potent inhibition of c-Src and Abl by compounds that recognize inactive kinase conformations

PDB Details

PDB ID
3G6G
Status
CURRENT
Deposition Date
2009-02-06
Modification Date
2011-07-13
Pubmed ID
19276351
Method
X-RAY DIFFRACTION
Resolution (Å)
2.31
UniProt Accessions
P00523

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 0 15
A C DFG 1 15
A C PDIG 6 7
A N ATP 0 18
A N MPP 3 14
A N ATP 4 12
A N DFG 5 6
A N MPP 7 5
B C CMP 1 17
B C EDI 3 11
B C DFG 4 11
B C PDIG 8 3
B N ATP 0 18
B N MPP 1 16
B N ATP 2 16
B N DFG 5 10

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Legend

Color Name Hit Count