Discovery of 3H-benzo[4,5]thieno[3,2-d]pyrimidin-4-ones as Potent, Highly Selective and Orally Bioavailable Pim Kinases Inhibitors

PDB Details

PDB ID
3JY0
Status
CURRENT
Deposition Date
2009-09-21
Modification Date
2009-11-10
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C DRS 2 16
A C PDIG 3 15
A C CMP 4 12
A C PDIG 6 2
A N ATP 0 17
A N DFG 3 13
A N DFG 4 11
A N ATP 6 8

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count