Structures of human Bruton's tyrosine kinase in active and inactive conformations suggests a mechanism of activation for TEC family kinases.

PDB Details

PDB ID
3K54
Status
CURRENT
Deposition Date
2009-10-06
Modification Date
2011-07-13
Pubmed ID
20052711
Method
X-RAY DIFFRACTION
Resolution (Å)
1.94
UniProt Accessions
Q06187

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 1 15
A C CMP 7 5
A C AAS 9 3
A N MPP 0 24
A N ATP 1 16
A N DFG 3 13
A N ATP 4 8
A N ATP 6 5
A N MPP 8 2

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Legend

Color Name Hit Count