Identification, SAR Studies and X-ray Cocrystal Analysis of a Novel Furano-pyrimidine Aurora Kinase A Inhibitor

PDB Details

PDB ID
3K5U
Status
CURRENT
Deposition Date
2009-10-08
Modification Date
2010-10-13
Pubmed ID
20039358
Method
X-RAY DIFFRACTION
Resolution (Å)
2.35
UniProt Accessions
O14965

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 23
A C CMP 2 15
A C PDIG 4 7
A C EDI 8 4
A N MPP 0 25
A N PIF 1 19
A N ATP 2 16
A N MT3 5 9

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Legend

Color Name Hit Count