Crystal structure of TGFbRI complexed with a pyrazolone inhibitor

PDB Details

PDB ID
3KCF
Status
CURRENT
Deposition Date
2009-10-21
Modification Date
2010-02-23
Pubmed ID
19914068
Method
X-RAY DIFFRACTION
Resolution (Å)
2.8
UniProt Accessions
P36897

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 14
A C AAS 2 14
A C LBP 3 11
A C AAS 7 4
A N ATP 0 15
A N ATP 1 15
A N ATP 9 2
A N DFG 10 2
A N DFG 11 2
B C DRS 3 10
B C AAS 5 9
B C LBP 6 6
B N ATP 0 18
B N ATP 2 12
B N DFG 8 5
B N DFG 10 2
C C AAS 5 9
C C LBP 9 2
C N ATP 0 17
C N ATP 3 13
C N DFG 6 7
D C AAS 0 14
D C EDI 1 13
D C LBP 3 12
D C DRS 9 3
D N ATP 0 17
D N ATP 2 14
D N DFG 5 9
E C LBP 1 12
E C AAS 5 9
E C DRS 10 3
E N ATP 0 16
E N ATP 2 13
E N DFG 4 12
E N ATP 8 2

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Legend

Color Name Hit Count