3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3

PDB Details

PDB ID
3L1S
Status
CURRENT
Deposition Date
2009-12-14
Modification Date
2010-09-08
Pubmed ID
20138514
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
P49841

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 1 19
A C PDIG 2 10
A C PDIG 5 6
A C DRS 6 6
A C EDI 7 4
A N MT3 3 15
A N ATP 4 13
A N ATP 5 9
B C PDIG 5 7
B C DRS 6 5
B N ATP 1 18
B N MT3 4 8

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Legend

Color Name Hit Count