Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

PDB Details

PDB ID
3LXL
Status
CURRENT
Deposition Date
2010-02-25
Modification Date
2010-07-28
Pubmed ID
20478313
Method
X-RAY DIFFRACTION
Resolution (Å)
1.74
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 2 16
A C CMP 4 11
A C LBP 7 3
A N MT3 1 16
A N DFG 3 10
A N ATP 4 9
A N MPP 9 2

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Legend

Color Name Hit Count