Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

PDB Details

PDB ID
3OW3
Status
CURRENT
Deposition Date
2010-09-17
Modification Date
2010-11-24
Pubmed ID
20971641
Method
X-RAY DIFFRACTION
Resolution (Å)
1.9
UniProt Accessions
P05132

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 0 25
A C PMP 5 8
A C PMP 6 4
A N ATP 1 12
A N ATP 3 12
A N PIF 4 12
A N DFG 6 4
A N ATP 7 3

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Legend

Color Name Hit Count