Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

PDB Details

PDB ID
3OW4
Status
CURRENT
Deposition Date
2010-09-17
Modification Date
2010-11-24
Pubmed ID
20971641
Method
X-RAY DIFFRACTION
Resolution (Å)
2.6
UniProt Accessions
P31749

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 1 21
A C DRS 3 10
A C PMP 5 4
A N ATP 0 22
A N PIF 3 11
A N ATP 6 8
B C PDIG 1 21
B C DRS 4 9
B C PMP 6 5
B N PIF 0 21
B N ATP 3 15
B N ATP 6 4

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count