Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589

PDB Details

PDB ID
3OY3
Status
CURRENT
Deposition Date
2010-09-22
Modification Date
2010-12-22
Pubmed ID
21118377
Method
X-RAY DIFFRACTION
Resolution (Å)
1.95
UniProt Accessions
P00520

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 0 18
A C AAS 2 13
A C DFG 3 9
A C AAS 4 7
A C ATP 8 4
A C CMP 11 3
A N MPP 0 21
A N ATP 2 16
A N ATP 4 7
A N MPP 5 5
A N MPP 8 4
B C ATP 2 13
B C AAS 3 10
B C AAS 4 8
B C DFG 5 7
B C DRS 7 6
B C CMP 8 5
B C DFG 9 3
B N ATP 0 17
B N MPP 2 16
B N ATP 5 7
B N MPP 6 6

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.

Legend

Color Name Hit Count