Crystal structure of BTK kinase domain complexed with 3-(2,6-Dichloro-phenyl)-7-[4-(2-diethylamino-ethoxy)-phenylamino]-1-methyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one

PDB Details

PDB ID
3PJ1
Status
CURRENT
Deposition Date
2010-11-08
Modification Date
2011-04-27
Pubmed ID
21280133
Method
X-RAY DIFFRACTION
Resolution (Å)
2.0
UniProt Accessions
Q06187

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 5 6
A C AAS 7 5
A N MPP 1 15
A N ATP 3 15
A N DFG 5 12
A N ATP 6 5
A N MPP 7 3
A N MPP 8 1

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Legend

Color Name Hit Count