Crystal structure of BTK kinase domain complexed with 2-[4-(2-Diethylamino-ethoxy)-phenylamino]-6-(4-fluoro-phenoxy)-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

PDB Details

PDB ID
3PJ2
Status
CURRENT
Deposition Date
2010-11-08
Modification Date
2011-04-27
Pubmed ID
21280133
Method
X-RAY DIFFRACTION
Resolution (Å)
1.75
UniProt Accessions
Q06187

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 3 12
A C AAS 6 5
A N MPP 0 16
A N MPP 1 15
A N MT3 2 13
A N ATP 3 12
A N PIF 4 10
A N PIF 5 9
A N ATP 6 8
A N PIF 7 8

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Legend

Color Name Hit Count