Crystal structure of BTK kinase domain complexed with 2-Methyl-5-[(E)-(3-phenyl-acryloyl)amino]-N-(2-phenyl-3H-imidazo[4,5-b]pyridin-6-yl)-benzamide

PDB Details

PDB ID
3PJ3
Status
CURRENT
Deposition Date
2010-11-08
Modification Date
2011-04-27
Pubmed ID
21280133
Method
X-RAY DIFFRACTION
Resolution (Å)
1.85
UniProt Accessions
Q06187

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 1 17
A C AAS 6 5
A N ATP 0 19
A N ATP 1 17
A N MPP 2 17
A N DFG 3 16
A N MPP 4 8
A N MPP 5 7
A N MPP 7 5

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Legend

Color Name Hit Count