Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family

PDB Details

PDB ID
3PJC
Status
CURRENT
Deposition Date
2010-11-09
Modification Date
2011-09-28
Pubmed ID
21155605
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
P52333

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 2 15
A C LBP 8 3
A N MT3 0 21
A N MPP 1 16
A N ATP 3 11
A N ATP 4 10

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Legend

Color Name Hit Count