Design, synthesis, and biological evaluation of pyrazolopyridine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (Part I)

PDB Details

PDB ID
3R22
Status
CURRENT
Deposition Date
2011-03-11
Modification Date
2012-02-29
Pubmed ID
21798738
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
O14965

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 3 10
A C CMP 5 9
A C PDIG 7 4
A C CMP 9 2
A N ATP 0 19
A N MT3 1 15
A N MPP 2 14
A N MPP 4 14
A N MT3 7 3

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Legend

Color Name Hit Count