Novel Isoquinolone PDK1 Inhibitors Discovered through Fragment-Based Lead Discovery

PDB Details

PDB ID
3SC1
Status
CURRENT
Deposition Date
2011-06-06
Modification Date
2011-10-26
Pubmed ID
21779981
Method
X-RAY DIFFRACTION
Resolution (Å)
2.7
UniProt Accessions
O15530

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 1 17
A C DRS 4 13
A N PIF 0 19
A N ATP 2 15

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Legend

Color Name Hit Count