Structural basis of Jak2 inhibition by the type II inhibtor NVP-BBT594

PDB Details

PDB ID
3UGC
Status
CURRENT
Deposition Date
2011-11-02
Modification Date
2012-08-29
Pubmed ID
22684457
Method
X-RAY DIFFRACTION
Resolution (Å)
1.34
UniProt Accessions
O60674

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 5 10
A C DFG 7 4
A N PIF 0 19
A N MT3 3 11
A N ATP 5 9
A N ATP 6 6
A N ATP 7 3
A N DFG 9 2

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Legend

Color Name Hit Count