Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indazol-3-yl)methylene]-6-methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one

PDB Details

PDB ID
3UMW
Status
CURRENT
Deposition Date
2011-11-14
Modification Date
2012-10-03
Pubmed ID
22540945
Method
X-RAY DIFFRACTION
Resolution (Å)
2.08
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 17
A C DRS 2 12
A C CMP 5 6
A C PDIG 6 5
A C DRS 7 5
A C LBP 8 5
A C LBP 9 4
A N MT3 0 25
A N MT3 1 17
A N ATP 3 14
A N ATP 4 8
A N DFG 7 3

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Legend

Color Name Hit Count