Discovery of Novel Allosteric MEK Inhibitors Possessing Classical and Non-classical Bidentate Ser212 Interactions.

PDB Details

PDB ID
3V01
Status
CURRENT
Deposition Date
2011-12-07
Modification Date
2012-07-18
Pubmed ID
22506516
Method
X-RAY DIFFRACTION
Resolution (Å)
2.7
UniProt Accessions
Q02750

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C MT3 1 16
A C CMP 3 12
A C DRS 6 7
A N MPP 0 20
A N MT3 2 17
A N ATP 3 15
A N MT3 4 11
A N MPP 5 7

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Legend

Color Name Hit Count