Discovery of Novel Allosteric MEK Inhibitors Possessing Classical and Non-classical Bidentate Ser212 Interactions.

PDB Details

PDB ID
3V04
Status
CURRENT
Deposition Date
2011-12-07
Modification Date
2012-07-18
Pubmed ID
22506516
Method
X-RAY DIFFRACTION
Resolution (Å)
2.7
UniProt Accessions
Q02750

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C MT3 1 20
A C CMP 4 12
A C DRS 5 5
A N MPP 0 22
A N MT3 1 16
A N ATP 2 15
A N MT3 4 9

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Legend

Color Name Hit Count