Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

PDB Details

PDB ID
3VBQ
Status
CURRENT
Deposition Date
2012-01-02
Modification Date
2012-05-16
Pubmed ID
22339127
Method
X-RAY DIFFRACTION
Resolution (Å)
1.85
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 19
A C CMP 4 11
A C PDIG 5 5
A C PDIG 8 2
A C LBP 9 2
A N MT3 1 15
A N MT3 2 12
A N DFG 5 9
A N ATP 6 8
A N ATP 7 6
A N ATP 8 6

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Legend

Color Name Hit Count