Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

PDB Details

PDB ID
3VBT
Status
CURRENT
Deposition Date
2012-01-02
Modification Date
2012-05-16
Pubmed ID
22339127
Method
X-RAY DIFFRACTION
Resolution (Å)
2.23
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 17
A C DRS 2 13
A C LBP 5 6
A C PDIG 6 4
A C CMP 7 3
A C LBP 9 2
A N ATP 1 14
A N MT3 3 13
A N MT3 4 12
A N DFG 6 8
A N ATP 8 3

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Legend

Color Name Hit Count