Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

PDB Details

PDB ID
3VBV
Status
CURRENT
Deposition Date
2012-01-02
Modification Date
2012-05-16
Pubmed ID
22339127
Method
X-RAY DIFFRACTION
Resolution (Å)
2.08
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C DRS 2 14
A C CMP 3 13
A C PDIG 5 10
A C PDIG 7 2
A C LBP 8 2
A N MT3 0 23
A N ATP 1 22
A N ATP 2 12
A N DFG 3 12
A N ATP 6 4

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Legend

Color Name Hit Count