Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

PDB Details

PDB ID
3VBX
Status
CURRENT
Deposition Date
2012-01-02
Modification Date
2012-05-16
Pubmed ID
22339127
Method
X-RAY DIFFRACTION
Resolution (Å)
2.03
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 19
A C CMP 2 12
A C DRS 4 9
A C LBP 7 5
A C PDIG 8 3
A C LBP 9 3
A N DFG 0 19
A N ATP 2 14
A N ATP 4 8
A N MT3 5 8
A N DFG 6 8
A N ATP 9 2

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Legend

Color Name Hit Count