Exploitation of hydrogen bonding constraints and flat hydrophobic energy landscapes in Pim-1 kinase needle screening and inhibitor design

PDB Details

PDB ID
3VC4
Status
CURRENT
Deposition Date
2012-01-03
Modification Date
2012-05-16
Pubmed ID
22339127
Method
X-RAY DIFFRACTION
Resolution (Å)
2.23
UniProt Accessions
P11309

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 17
A C PDIG 3 10
A C DRS 4 10
A C LBP 5 7
A C CMP 7 5
A C DRS 9 4
A C PDIG 10 2
A N ATP 0 22
A N DFG 1 16
A N ATP 4 9
A N MT3 6 5
A N ATP 8 2

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count